Cdc25B(Phospho Ser353) Polyclonal Antibody, 20ul Molecular Sciences The shorter isoform has been

The shorter isoform has been shown to display weaker transforming activity

It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway

Beta subunits are important regulators of alpha subunits

Tissue specific transplantation antigen P35B is a NADP (H)-binding protein

Several alternatively spliced transcript variants have been observed

Cdc25B(Phospho Ser353) Polyclonal Antibody, 20ul Molecular Sciences The shorter isoform has beenCDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in