IP3R-I(Phospho Ser1598) Polyclonal Antibody, 100ul Long RNA Synthesis A secreted isoform is involved

A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines

This receptor is highly expressed during embryonic development

which is associated with neuronal death in Alzheimer's disease

a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1)

This protein is a component of anaphase-promoting complex (APC)

IP3R-I(Phospho Ser1598) Polyclonal Antibody, 100ul Long RNA Synthesis A secreted isoform is involvedThis gene encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.