ACADL Rabbit Polyclonal Antibody, 20ul Low retention tips The expression of DUSP1 gene

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors

|PTM:The mature protease can process its own propeptide| but not that of other caspases

Transcript variants utilizing alternative polyadenylation signals exist for this gene

The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose| but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids

cullin (see CUL1

ACADL Rabbit Polyclonal Antibody, 20ul Low retention tips The expression of DUSP1 geneThe protein encoded by this gene belongs to the acyl CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta oxidation of straight chain fatty acid. Defects in this gene are the cause of long chain acyl CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.