CD56 Polyclonal Antibody, 100ul[BT-AP02459] Lentiviral Packaging The protein encoded by DOK2

The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

It functions as the main mediator of VEGF-induced endothelial proliferation| survival| migration| tubular morphogenesis and sprouting

a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs

The chromosomal rearrangements are the most common genetic alterations in this gene| which result in creation of multiple fusion genes in tumourigenesis| including ALK (chromosome 2)/EML4 (chromosome 2)| ALK/RANBP2 (chromosome 2)| ALK/ATIC (chromosome 2)| ALK/TFG (chromosome 3)| ALK/NPM1 (chromosome 5)| ALK/SQSTM1 (chromosome

The receptors of IL15 and IL2 share two subunits

CD56 Polyclonal Antibody, 100ul[BT-AP02459] Lentiviral Packaging The protein encoded by DOK2KRT10 encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in KRT10 are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of