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GDF-8 Polyclonal Antibody, 100ul Filtration Several alternatively spliced transcript variants

SKU: 7039589390

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GDF-8 Polyclonal Antibody, 100ul Filtration Several alternatively spliced transcript variantsMSTN encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and

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Description

Several alternatively spliced transcript variants of this gene have been reported

Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues

Dok-5 transcript is abundant in muscle and increases during T cell activation

and may be involved in TP53 induced apoptosis

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells

GDF-8 Polyclonal Antibody, 100ul Filtration Several alternatively spliced transcript variantsMSTN encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and

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