Hox-B9 Polyclonal Antibody, 50ul ADME Mutations in CUBN may play

Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia

The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles

a nucleation core

This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body

Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene

Hox-B9 Polyclonal Antibody, 50ul ADME Mutations in CUBN may playHOXB9 is a member of the Abd B homeobox family and encodes a protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. Homeobox protein Hox B9 functions as a sequence specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.