TIRAP(Phospho Tyr86) Polyclonal Antibody, 100ul Cell Culture Dishes The iron-sulfur protein fraction of

The iron-sulfur protein fraction of complex I is made up of 7 subunits

Mutations in ITPR1 cause spinocerebellar ataxia type 15

Amplification and/or overexpression of this gene has been reported in numerous cancers

The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop

or changes in metabolism

TIRAP(Phospho Tyr86) Polyclonal Antibody, 100ul Cell Culture Dishes The iron-sulfur protein fraction ofThe innate immune system recognizes microbial pathogens through Toll like receptors (TLRs), which identify pathogen associated molecular patterns. Different TLRs recognize different pathogen associated molecular patterns and all TLRs have a Toll interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It