SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in this gene have

Mutations in this gene have been associated with several diseases

Transcripts of this gene have been reported in specimens of human testis

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

which is several orders of magnitude faster than conventional molecular motor proteins

The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells

SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in this gene haveThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding