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IKK gamma(Phospho Ser31) Polyclonal Antibody, 50ul 3D Culture This gene may be involved

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IKK gamma(Phospho Ser31) Polyclonal Antibody, 50ul 3D Culture This gene may be involvedThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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Description

This gene may be involved in coronary artery disease and in the pathogenesis of sepsis

Caspase 8 was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls

May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal

and thus may function as a regulator of GGT II activity

Although the protein encoded by this gene shares strong homology with members of the MAGE family

IKK gamma(Phospho Ser31) Polyclonal Antibody, 50ul 3D Culture This gene may be involvedThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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