Tau (Acetyl Lys686) Polyclonal Antibody, 20ul Thermal Control Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been identified for this gene

A pseudogene of this gene is located on the X chromosome

Translocations between this gene and many other partner genes have been observed in different leukemias

This protein is involved in cell adhesion

and may be instrumental in the execution of apoptosis following caspase activation

Tau (Acetyl Lys686) Polyclonal Antibody, 20ul Thermal Control Several alternatively spliced transcript variantsThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,