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LRRK2 Polyclonal Antibody, 50ul Miscellaneous This receptor associates with guanine-nucleotide-binding

SKU: 6921439331

4.3
PLN162.00 PLN200.00

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LRRK2 Polyclonal Antibody, 50ul Miscellaneous This receptor associates with guanine-nucleotide-bindingThis gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.

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Description

This receptor associates with guanine-nucleotide-binding (G) proteins

It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin

sequences which confer targeted degradation to those proteins which contain them

Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains

and acts as a tumor suppressor in hepatoma cells

LRRK2 Polyclonal Antibody, 50ul Miscellaneous This receptor associates with guanine-nucleotide-bindingThis gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.

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