APC4 Polyclonal Antibody, 50ul Immuno Plates ZC3H8 is a Protein Coding

ZC3H8 is a Protein Coding gene

The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels

and a pseudogene of this gene is located on the long arm of chromosome 12

Mutations in this gene cause aminoacylase-1 deficiency| a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids

The protein encoded by this gene is part of the Mediator complex| which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes

APC4 Polyclonal Antibody, 50ul Immuno Plates ZC3H8 is a Protein CodingA large protein complex, termed the anaphase promoting complex (APC), or the cyclosome, promotes metaphase anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of