BUB1 Polyclonal Antibody, 100ul[BT-AP01009] Gel & Buffers Chromosome 7 has been linked

Chromosome 7 has been linked to Osteogenesis imperfecta

The ADP ribosylation factor GTPase activating protein 3 encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins

due to defective resorption of immature bone

the conversion of nucleosomal chromatin to the compact

which are microtubule-based structures thought to help organize centrosomes

BUB1 Polyclonal Antibody, 100ul[BT-AP01009] Gel & Buffers Chromosome 7 has been linkedBUB1 (BUB1 mitotic checkpoint serine threonine kinase) encodes a serine threonine protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex cyclosome. This protein may also function in the DNA damage response. Mutations in BUB1