Acetyl-EPAS-1 (K385) Polyclonal Antibody, 100ul Mechanical Pipette but is the most active

but is the most active as a retinol dehydrogenase

it is thought that the presenilins are involved in the cleavage of the Notch receptor such that

GO annotations related to this gene include chromatin binding and transcriptional activator activity

There is a pseudogene for TCEAL4 on chromosome 13

due to the N-terminal 1-49 amino acid sequence that could be cut down

Acetyl-EPAS-1 (K385) Polyclonal Antibody, 100ul Mechanical Pipette but is the most activeEPAS1 (endothelial PAS domain protein 1) encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic helix loop helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in EPAS1 are associated with erythrocytosis familial type 4.