HMGN1/2/3/4 Rabbit Polyclonal Antibody, 100ul Cell Proliferation Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been found for CDK10

Several alternatively spliced transcript variants have been noted for CASP12

Mitogen-activated protein kinase kinase kinase MLT

thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1

A related family member

HMGN1/2/3/4 Rabbit Polyclonal Antibody, 100ul Cell Proliferation Multiple transcript variants encoding differentThe protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein HMG17 the encoded protein may help maintain an open chromatin configuration around transcribable genes.