ET-1 Polyclonal Antibody, 100ul Cell Biology and migration

and migration

The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity

May function in nuclear protein import as nuclear transport receptor

Mutations in this gene have been associated with geroderma osteodysplastica

and other APC complex proteins

ET-1 Polyclonal Antibody, 100ul Cell Biology and migrationEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.