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p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11723] Lysosome Gene expression is high during

SKU: 68036969756

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p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11723] Lysosome Gene expression is high duringThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

Gene expression is high during fetal development and in most tumors| yet low in adult tissues

and damage to the mucus layer in the lung

and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins

metabolic control

Three transcript variants encoding three different isoforms have been found for this gene

p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11723] Lysosome Gene expression is high duringThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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