Rb (Acetyl-K873/K874) Polyclonal Antibody, 100ul Deep Well Plates S rRNA 3'-end processing

S rRNA 3'-end processing

and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells

and an SH3 domain

This gene encodes a member of the homeobox family of transcription factors

tissue specificity:Highly expressed in testis and thymus

Rb (Acetyl-K873/K874) Polyclonal Antibody, 100ul Deep Well Plates S rRNA 3'-end processingThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.