MSK2(Phospho Thr568) Polyclonal Antibody, 100ul Stepper Inhibits SIRT1 in a CHEK2

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

The solute carrier family 27 member 5 encoded by SLC27A5 is an isozyme of very long-chain acyl-CoA synthetase (VLCS)

The protein consists of a tetramer of identical subunits

indicating that the encoded protein might also represent a transcription factor

This protein functions as a monomer

MSK2(Phospho Thr568) Polyclonal Antibody, 100ul Stepper Inhibits SIRT1 in a CHEK2This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine threonine kinases. This kinase contains 2 non identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene.