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Cytokeratin 18(Phospho Ser33) Polyclonal Antibody, 100ul Multi-Layer Cell Culture System and environmental stresses

SKU: 6710714443

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Cytokeratin 18(Phospho Ser33) Polyclonal Antibody, 100ul Multi-Layer Cell Culture System and environmental stressesKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

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Description

and environmental stresses

Defects in this gene may be a cause of autosomal recessive spinocerebellar ataxia-10

which can result in thrombosis or embolism

The encoded protein is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide

Weakly expressed in lung

Cytokeratin 18(Phospho Ser33) Polyclonal Antibody, 100ul Multi-Layer Cell Culture System and environmental stressesKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

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