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CEAM6 Polyclonal Antibody, 50ul[BT-AP01468] Cell Senescence Studies using mouse models of

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CEAM6 Polyclonal Antibody, 50ul[BT-AP01468] Cell Senescence Studies using mouse models ofThis gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent

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Description

Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS

NDUFS5 is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family

The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions

This protein can interact with the check point protein RAD1 but not with RAD9

or ITIM (see MIM 604964)

CEAM6 Polyclonal Antibody, 50ul[BT-AP01468] Cell Senescence Studies using mouse models ofThis gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent

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