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SREBP-1 Polyclonal Antibody, 50ul[BT-AP08552] Apoptosis & Autophagy Mutations in this gene may

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SREBP-1 Polyclonal Antibody, 50ul[BT-AP08552] Apoptosis & Autophagy Mutations in this gene maySREBF1 encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by

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Description

Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes

It binds to vitamin D and its plasma metabolites and transports them to target tissues

The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1

Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression| and the zinc-fingers comprise the DNA binding domain

ATF3 encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors

SREBP-1 Polyclonal Antibody, 50ul[BT-AP08552] Apoptosis & Autophagy Mutations in this gene maySREBF1 encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by

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