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IGF-IR(Phospho Tyr1346) Polyclonal Antibody, 50ul Culture Tubes and interleukin 5 (IL5)

SKU: 66236874494

4.4
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IGF-IR(Phospho Tyr1346) Polyclonal Antibody, 50ul Culture Tubes and interleukin 5 (IL5)This receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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Description

and interleukin 5 (IL5)

There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites

and intracellular protein trafficking

This protein may function in regulating cellular stress responses

This protein may play a role in negatively regulating cell differentiation

IGF-IR(Phospho Tyr1346) Polyclonal Antibody, 50ul Culture Tubes and interleukin 5 (IL5)This receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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