LIMK-2 Polyclonal Antibody, 50ul[BT-AP05020] Centrifuges Chromosomal translocations in non-Hodgkin's lymphoma

Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3

G3BP2 has been shown to interact with IκBα

and to activate JNK signaling pathway when overexpressed in cells

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An important paralog of this gene is RPL7

LIMK-2 Polyclonal Antibody, 50ul[BT-AP05020] Centrifuges Chromosomal translocations in non-Hodgkin's lymphomaThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase