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LTOR3 Polyclonal Antibody, 20ul Microbial Genome Editing Belongs to the fibroblast growth

SKU: 6546928199

4.3
USD97.20 USD144.20

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LTOR3 Polyclonal Antibody, 20ul Microbial Genome Editing Belongs to the fibroblast growthThis gene encodes a scaffold protein that functions in the extracellular signal regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen activated protein binding protein interacting protein, and binds specifically to MAP kinase kinase MAP2K1 MEK1, MAP kinase MAPK3 ERK1, and MAP kinase MAPK1 ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation.

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Description

Belongs to the fibroblast growth factor-binding protein family

Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH)

The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop

This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1)

PXN (paxillin) encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion)

LTOR3 Polyclonal Antibody, 20ul Microbial Genome Editing Belongs to the fibroblast growthThis gene encodes a scaffold protein that functions in the extracellular signal regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen activated protein binding protein interacting protein, and binds specifically to MAP kinase kinase MAP2K1 MEK1, MAP kinase MAPK3 ERK1, and MAP kinase MAPK1 ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation.

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