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NEC1 Rabbit Polyclonal Antibody, 100ul Glassware This gene encodes a 105

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NEC1 Rabbit Polyclonal Antibody, 100ul Glassware This gene encodes a 105This gene encodes a member of the subtilisin like proprotein convertase family which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the

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Description

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein

Several upstream open reading frames (uORFs) have been identified| which repress the translation of the dORF| and two of which can encode small mitochondrial membrane proteins

The gamma subunits contain the active site of the enzyme

each encoding a distinct carboxyl terminus

This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism| synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney

NEC1 Rabbit Polyclonal Antibody, 100ul Glassware This gene encodes a 105This gene encodes a member of the subtilisin like proprotein convertase family which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the

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