PMS2/PMS2CL Polyclonal Antibody, 100ul Pipette Filler This endonuclease catalyzes the first

This endonuclease catalyzes the first step in RNA splicing which is the removal of introns

The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A| 3A and 4A| and may play a role in intracellular vesicle trafficking

It contains an F-box motif and seven conserved helicase motifs| and has both DNA-dependent ATPase and DNA unwinding activities

is of considerable interest to the pharmaceutical industry

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein

PMS2/PMS2CL Polyclonal Antibody, 100ul Pipette Filler This endonuclease catalyzes the firstThe protein encoded by PMS2 (PMS1 homolog 2, mismatch repair system component) is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL alpha heterodimer. The MutL alpha heterodimer possesses an endonucleolytic