SLIK2 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in CDKN1C are implicated

Mutations in CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome

which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway

There is a pseudogene for this gene on chromosome 13

spherophakia

Isoform 1 is expressed in liver at very low levels

SLIK2 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in CDKN1C are implicatedThis gene encodes an integral membrane protein that contains two N terminal leucine rich repeats domains and contains C terminal regions similar to neurotrophin receptors. The encoded protein may play a role in modulating neurite activity. Alternatively spliced transcript variants encoding the same protein have been described.