Human E3 Ubiquitin-protein Ligase Amfr, AMFR ELISA Kit, 96T 3D Cell Culture Consumables Has both folate hydrolase and
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Human E3 Ubiquitin-protein Ligase Amfr, AMFR ELISA Kit, 96T 3D Cell Culture Consumables Has both folate hydrolase andE3 ubiquitin protein ligase that mediates the polyubiquitination of lysine and cysteine residues on target proteins, such as CD3D, CYP3A4, CFTR, INSIG1, SOAT2 ACAT2 and APOB for proteasomal degradation (PubMed: 10456327, PubMed: 11724934, PubMed: 12670940, PubMed: 19103148, PubMed: 24424410, PubMed: 28604676). Component of a VCP p97 AMFR gp78 complex that participates in the final step of endoplasmic reticulum associated degradation (ERAD) (PubMed:
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