c-Kit(Phospho-Tyr823) Rabbit Polyclonal Antibody, 50ul Plasmid Preparation This protein is localized to

This protein is localized to the centrosome

consists of a homodimer

and thus provides a selective advantage in tumorigenesis

This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain| which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor

resulting in the creation of an N-terminal chain and the corresponding C-terminal chain

c-Kit(Phospho-Tyr823) Rabbit Polyclonal Antibody, 50ul Plasmid Preparation This protein is localized toThis gene encodes the human homolog of the proto oncogene c kit. C kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors mast cell disease acute myelogenous lukemia and piebaldism. Multiple transcript variants encoding