p47-phox Polyclonal Antibody, 100ul[BT-AP06795] Thermal Control The protein encoded by this

The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion

all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases

Alternatively spliced variants encoding different isoforms have been identified

It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane

It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human

p47-phox Polyclonal Antibody, 100ul[BT-AP06795] Thermal Control The protein encoded by thisNeutrophil cytosolic factor 1 encoded by NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.