GPVI Polyclonal Antibody, 100ul Immunoassays HAAO catalyzes the synthesis of

HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid

Pseudogenes of this gene are located on the long arms of chromosomes 1

The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins| which also contain an N-terminal pleckstrin homology domain

The encoded protein plays a role in the inducible expression of cytokine genes in T cells| especially in the induction of interleukin-2 and interleukin-4

Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome

GPVI Polyclonal Antibody, 100ul Immunoassays HAAO catalyzes the synthesis ofThis gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet type bleeding disorder 11