SENP1 Polyclonal Antibody, 20ul Drug Development and Evaluation Overexpression of CDCA7 is found

Overexpression of CDCA7 is found to enhance the transformation of lymphoblastoid cells

including five of the six minichromosome maintenance (Mcm) proteins and the p180 subunit of DNA polymerase α-primase

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but not the tumorogenicity

The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments

SENP1 Polyclonal Antibody, 20ul Drug Development and Evaluation Overexpression of CDCA7 is foundSENP1 encodes a cysteine protease that specifically targets members of the small ubiquitin like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.