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MDM1 Polyclonal Antibody, 50ul Plasma this gene may play a

SKU: 63407194256

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SEK185.00 SEK227.00

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MDM1 Polyclonal Antibody, 50ul Plasma this gene may play aMDM1 (Mdm1 nuclear protein) encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for MDM1.

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Description

this gene may play a role in the Down Syndrome phenotype

It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes

endonuclease catalytic subunit encoded by ERCC4 forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair

The mouse gene is located in double minute (DM) chromatin particles

They are stable secretory proteins expressed in gastrointestinal mucosa

MDM1 Polyclonal Antibody, 50ul Plasma this gene may play aMDM1 (Mdm1 nuclear protein) encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for MDM1.

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