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Garlics potential effect on HCy levels has been reported in a small clinical trial of atherosclerosis patients randomized to aged garlic extract ( P =0.08).127 Additionally, in an animal model of HHCy, induced by a severely folate-depleted diet in rats, aged garlic extract decreased plasma HCy concentrations by 30%.128 In contrast, elevated levels of HCy caused by mild folate deficiency did not change significantly by garlic supplementation.128 Thus, garlic may have an effect on HCy metabolism independent of the effect of B vitamins in addition to boosting H 2 S production

MT-II-induced pro-erectile and pro-social effects are substantially mediated through MC4R activation of oxytocinergic neurones in the paraventricular nucleus , and research has used MT-II to characterise the melanocortin-oxytocin pathway axis

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