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EI2BE Polyclonal Antibody, 100ul Pasteur Pipets DM plays a central role

SKU: 63330269147

4.1
PLN123.75 PLN172.75

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EI2BE Polyclonal Antibody, 100ul Pasteur Pipets DM plays a central roleThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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Description

DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site

medulloblastoma (MDB)

Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms

and facilitating tissue invasion

likely interacting with roundabout homolog receptors to effect cell migration

EI2BE Polyclonal Antibody, 100ul Pasteur Pipets DM plays a central roleThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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