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CD58 Polyclonal Antibody, 50ul[BT-AP01934] Organelle Studies The hexameric protein complex formed

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CD58 Polyclonal Antibody, 50ul[BT-AP01934] Organelle Studies The hexameric protein complex formedITIH1 encodes a member of the inter alpha trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter alpha trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and

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Description

The hexameric protein complex formed by the mini-chromosome maintenance proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins

Also expressed by dermal Langerhans cells (at protein level)

with oxidized glutatione

Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane

Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections

CD58 Polyclonal Antibody, 50ul[BT-AP01934] Organelle Studies The hexameric protein complex formedITIH1 encodes a member of the inter alpha trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter alpha trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and

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