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VRK3 Polyclonal Antibody, 50ul Cell Culture Plates FGF receptor substrates (FRS2 and

SKU: 63292829054

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VRK3 Polyclonal Antibody, 50ul Cell Culture Plates FGF receptor substrates (FRS2 andVRK3 (vaccinia related kinase 3) encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. In both human and mouse, VRK3 has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. VRK3 is widely

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Description

FGF receptor substrates (FRS2 and FRS3) are key adaptor proteins that mediate FGF-FGFR signalling in benign as well as malignant tissue

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable)| together with a carnitine-acylcarnitine translocase

The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER)

and serotonin

This protein has been shown to specifically interact with BCL10

VRK3 Polyclonal Antibody, 50ul Cell Culture Plates FGF receptor substrates (FRS2 andVRK3 (vaccinia related kinase 3) encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. In both human and mouse, VRK3 has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. VRK3 is widely

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