FBX18 Rabbit Polyclonal Antibody, 50ul Gel & Buffers The results of the mouse

The results of the mouse knockout of the ortholog suggest that it is involved in numerous developmental processes

May play an important role in the developing brain and neuronal differentiation

Mutations in this gene cause Alexander disease

Cyclin dependent kinase inhibitor 1A mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli

but also as a potent signalling molecule

FBX18 Rabbit Polyclonal Antibody, 50ul Gel & Buffers The results of the mouseThis gene encodes a member of the F box protein family members of which are characterized by an approximately 40 amino acid motif the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into three classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs