ZMYM3 Rabbit Polyclonal Antibody, 50ul Microplate Mixer Peptidyl-prolyl cis-trans isomerase B encoded

Peptidyl-prolyl cis-trans isomerase B encoded by PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum

Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia

Interaction of this protein with eIF4E inhibits complex assembly and represses translation

suggesting a role in transcriptional regulation

and with systemic non-neuropathic amyloidosis

ZMYM3 Rabbit Polyclonal Antibody, 50ul Microplate Mixer Peptidyl-prolyl cis-trans isomerase B encodedThis gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X; 13) involving this gene is associated with X linked mental retardation. Several alternatively