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SEM6B Polyclonal Antibody, 50ul Human Genome Knockout Libraries autosomal recessive

SKU: 62652506401

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SEM6B Polyclonal Antibody, 50ul Human Genome Knockout Libraries autosomal recessiveThis gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development.

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Description

autosomal recessive

Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression| and the zinc-fingers comprise the DNA binding domain

The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat

Perfect for laboratory use

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

SEM6B Polyclonal Antibody, 50ul Human Genome Knockout Libraries autosomal recessiveThis gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development.

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