RAB8A Polyclonal Antibody, 100ul Cellular Function Assays extracellular ligands include parathyroid horomones

extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins

This protein is an essential element of the cyclin A-CDK2 S-phase kinase

Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism

This gene is an ortholog of the Drosophila fat gene

The encoded protein localizes to the inner mitochondrial membrane

RAB8A Polyclonal Antibody, 100ul Cellular Function Assays extracellular ligands include parathyroid horomonesThe protein encoded by this gene is a member of the RAS superfamily which are small GTP GDP binding proteins with an average size of 200 amino acids. The RAS related proteins of the RAB YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP GDP