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NCPR Polyclonal Antibody, 20ul 3D Culture CPZ (carboxypeptidase Z) encodes a

SKU: 62189899577

4.9
PLN97.20 PLN133.20

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NCPR Polyclonal Antibody, 20ul 3D Culture CPZ (carboxypeptidase Z) encodes aThis gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD binding domain and a flavodoxin like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal

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Description

CPZ (carboxypeptidase Z) encodes a member of the metallocarboxypeptidase family

also known as suppressor of cytokine signaling (SOCS)

Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency

A smaller fraction is cytoplasmic

tissue specificity:Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue

NCPR Polyclonal Antibody, 20ul 3D Culture CPZ (carboxypeptidase Z) encodes aThis gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD binding domain and a flavodoxin like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal

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