Histone H1 Polyclonal Antibody, 50ul[BT-AP03992] Plasma Tay-Sachs disease is a lethal

Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene

The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al

a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever

it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration

It contains a PR-domain and multiple zinc finger motifs

Histone H1 Polyclonal Antibody, 50ul[BT-AP03992] Plasma Tay-Sachs disease is a lethalHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.