BST-1 Polyclonal Antibody, 100ul[BT-AP00993] Insect Expression Mutations in CDKN1B are associated

Mutations in CDKN1B are associated with multiple endocrine neoplasia type IV (MEN4)

It activates its own transcription which may stabilize commitment to myogenesis

This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins

resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair

Binds DNA as an heterodimer with MAX

BST-1 Polyclonal Antibody, 100ul[BT-AP00993] Insect Expression Mutations in CDKN1B are associatedBone marrow stromal cell antigen 1 is a stromal cell line derived glycosylphosphatidylinositol anchored molecule that facilitates pre B cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the