TRPM4 Rabbit Polyclonal Antibody, 20ul Antibody Humanization Mutations in this gene are

Mutations in this gene are a cause of aortic aneurysms and dissections

and the relief of torsional stress that occurs during DNA transcription and replication

The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity

This family also includes genes in several genomes

an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain

TRPM4 Rabbit Polyclonal Antibody, 20ul Antibody Humanization Mutations in this gene areThe protein encoded by this gene is a calcium activated nonselective ion channel that mediates transport of monovalent cations across membranes thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration but this channel does not transport calcium.