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IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 100ul Thermo Mix results in a greater abundance

SKU: 61663859534

4.5
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IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 100ul Thermo Mix results in a greater abundanceThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

results in a greater abundance of the unspliced form of the transcript than the spliced form

Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures

Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli

MED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP

IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 100ul Thermo Mix results in a greater abundanceThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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