RPGF2 Polyclonal Antibody, 20ul Vector Construction NEURL4 exists as two alternatively

NEURL4 exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 17p13

DRAK1 and DRAK2 are localized to the nucleus

This gene is a member of an orphan homeobox-containing transcription factor family

and they serve as targets for the small GTP binding proteins Cdc42 and Rac

The expression of these transcripts is restricted to the salivary gland among the human tissues examined

RPGF2 Polyclonal Antibody, 20ul Vector Construction NEURL4 exists as two alternativelyMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000