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FAST Polyclonal Antibody, 50ul Contamination Detection & Removal This gene encodes a preproprotein

SKU: 61587285895

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FAST Polyclonal Antibody, 50ul Contamination Detection & Removal This gene encodes a preproproteinFas activated serine threonine kinase encoded by FASTK is a member of the serine threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found

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Description

This gene encodes a preproprotein that undergoes extensive| tissue-specific| post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases

which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes

Binds RAB11A that has been activated by GTP binding

Mutations in this gene cause Schwartz-Jampel syndrome type 2

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family

FAST Polyclonal Antibody, 50ul Contamination Detection & Removal This gene encodes a preproproteinFas activated serine threonine kinase encoded by FASTK is a member of the serine threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found

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