EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 20ul Antibody Humanization A mutation in the mouse

A mutation in the mouse ortholog of this gene results in homeotic| posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants

an essential step in the biosynthesis of PtdInsPs (Barylko et al

Binding to he LCK SH3 domain occurs constitutively

hypertriglyceridemia

The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene

EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 20ul Antibody Humanization A mutation in the mouseThis gene encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.